5UOE

Crystal Structure Analysis of Elbow-Engineered-Fab-Bound Human Insulin Degrading Enzyme (IDE)

Summary for 5UOE

• Entry DOI: 10.2210/pdb5uoe/pdb
• Descriptor: Insulin-degrading enzyme, FAB Heavy chain with engineered elbow, FAB light chain (3 entities in total)
• Functional Keywords: hydrolase, fab, elbow-engineer, hydrolase-immune system complex, hydrolase/immune system
• Biological source: Homo sapiens (Human); More
• Cellular location: Cytoplasm: P14735
• Total number of polymer chains: 15
• Total formula weight: 811092.93

Authors

Liang, W.G.,Bailey, L.,Kossiakoff, T.,Tang, W.J. (deposition date: 2017-01-31, release date: 2018-02-07, Last modification date: 2023-10-04)

• Primary citation: Liang, W.G.,Bailey, L.,Kossiakoff, T.,Tang, W.J.; Crystal Structure Analysis of Elbow-Engineered-Fab-Bound Human Insulin Degrading Enzyme (IDE); To Be Published,

Experimental method

X-RAY DIFFRACTION (3.8 Å)