5UEM
Crystal structure of 354NC37 Fab in complex with HIV-1 clade AE strain 93TH057 gp120
Summary for 5UEM
Entry DOI | 10.2210/pdb5uem/pdb |
Related | 5UEL |
Descriptor | clade A/E 93TH057 HIV-1 gp120 core, 354NC37 Fab Heavy Chain, 354NC37 Fab Light Chain, ... (9 entities in total) |
Functional Keywords | hiv, envelope protein, antibody, immunity, immune system |
Biological source | Human immunodeficiency virus 1 More |
Total number of polymer chains | 3 |
Total formula weight | 92209.13 |
Authors | Sievers, S.A.,Gristick, H.B.,Bjorkman, P.J. (deposition date: 2017-01-02, release date: 2018-01-10, Last modification date: 2023-10-04) |
Primary citation | Freund, N.T.,Wang, H.,Scharf, L.,Nogueira, L.,Horwitz, J.A.,Bar-On, Y.,Golijanin, J.,Sievers, S.A.,Sok, D.,Cai, H.,Cesar Lorenzi, J.C.,Halper-Stromberg, A.,Toth, I.,Piechocka-Trocha, A.,Gristick, H.B.,van Gils, M.J.,Sanders, R.W.,Wang, L.X.,Seaman, M.S.,Burton, D.R.,Gazumyan, A.,Walker, B.D.,West, A.P.,Bjorkman, P.J.,Nussenzweig, M.C. Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller. Sci Transl Med, 9:-, 2017 Cited by PubMed: 28100831DOI: 10.1126/scitranslmed.aal2144 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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