5TOY

X-Ray Crystal Structure of Ruthenocene Conjugated Penicilloate and Penilloate Products in Complex with CTX-M-14 E166A Beta-Lactamase

Summary for 5TOY

Entry DOI	10.2210/pdb5toy/pdb
Related PRD ID	PRD_900003
Descriptor	Beta-lactamase, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, POTASSIUM ION, ... (8 entities in total)
Functional Keywords	beta-lactamase, organometallic, ruthenocene, ctx-m-14, hydrolase-antibiotic complex, hydrolase/antibiotic
Biological source	Escherichia coli
Total number of polymer chains	2
Total formula weight	59537.11
Authors	Lewandowski, E.M.,Chen, Y. (deposition date: 2016-10-19, release date: 2017-11-08, Last modification date: 2023-10-04)
Primary citation	Lewandowski, E.M.,Lethbridge, K.G.,Sanishvili, R.,Skiba, J.,Kowalski, K.,Chen, Y. Mechanisms of proton relay and product release by Class A beta-lactamase at ultrahigh resolution. FEBS J., 285:87-100, 2018 Cited by PubMed: 29095570 DOI: 10.1111/febs.14315 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.3 Å)

Structure validation