5TE4
Crystal Structure of Broadly Neutralizing VRC01-class Antibody N6 in Complex with HIV-1 Clade G Strain X2088 gp120 Core
Summary for 5TE4
Entry DOI | 10.2210/pdb5te4/pdb |
Related | 5TE6 5TE7 |
Descriptor | HIV-1 clade G strain X2088 gp120, Heavy chain of antibody N6, Light chain of antibody N6, ... (8 entities in total) |
Functional Keywords | hiv-1, vrc01-class antibody, n6, cd4-binding site, gp120, immune system |
Biological source | Human immunodeficiency virus 1 More |
Total number of polymer chains | 3 |
Total formula weight | 91172.63 |
Authors | Zhou, T.,Kwong, P.D. (deposition date: 2016-09-20, release date: 2016-11-23, Last modification date: 2020-07-29) |
Primary citation | Huang, J.,Kang, B.H.,Ishida, E.,Zhou, T.,Griesman, T.,Sheng, Z.,Wu, F.,Doria-Rose, N.A.,Zhang, B.,McKee, K.,O'Dell, S.,Chuang, G.Y.,Druz, A.,Georgiev, I.S.,Schramm, C.A.,Zheng, A.,Joyce, M.G.,Asokan, M.,Ransier, A.,Darko, S.,Migueles, S.A.,Bailer, R.T.,Louder, M.K.,Alam, S.M.,Parks, R.,Kelsoe, G.,Von Holle, T.,Haynes, B.F.,Douek, D.C.,Hirsch, V.,Seaman, M.S.,Shapiro, L.,Mascola, J.R.,Kwong, P.D.,Connors, M. Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth. Immunity, 45:1108-1121, 2016 Cited by PubMed: 27851912DOI: 10.1016/j.immuni.2016.10.027 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.75 Å) |
Structure validation
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