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5TE4

Crystal Structure of Broadly Neutralizing VRC01-class Antibody N6 in Complex with HIV-1 Clade G Strain X2088 gp120 Core

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(G)
HIV-1 clade G strain X2088 gp120polymer36040188.31Pfam (PF00516)
UniProt (by SIFTS) (C6ZIH2)
Human immunodeficiency virus 1
2B
(H)
Heavy chain of antibody N6polymer22524188.31Homo sapiens (Human)
3C
(L)
Light chain of antibody N6polymer21023164.71Homo sapiens (Human)
4D, E, F, G, H...
(G, L)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.212Chemie (NAG)
5O, P, Q, S, T...
(G, H, L)
SULFATE IONnon-polymer96.18Chemie (SO4)
6R
(G)
(R,R)-2,3-BUTANEDIOLnon-polymer90.11Chemie (BU3)
7U
(H)
(4S)-2-METHYL-2,4-PENTANEDIOLnon-polymer118.21Chemie (MPD)
8AA, BA, Z
(H, L, G)
waterwater18.025Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight87541.3
Non-Polymers*Number of molecules22
Total formula weight3631.3
All*Total formula weight91172.6
*Water molecules are not included.

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PDB entries from 2024-11-06

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