5T5W
Structure of an affinity matured lambda-IFN/IFN-lambdaR1/IL-10Rbeta receptor complex
Summary for 5T5W
Entry DOI | 10.2210/pdb5t5w/pdb |
Descriptor | Interleukin-10 receptor subunit beta, Interferon lambda receptor 1, Interferon lambda-3, ... (5 entities in total) |
Functional Keywords | receptor, cytokine, cytokine-cytokine receptor complex, cytokine/cytokine receptor |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 70324.78 |
Authors | Mendoza, J.L.,Jude, K.M.,Garcia, K.C. (deposition date: 2016-08-31, release date: 2017-03-29, Last modification date: 2023-10-04) |
Primary citation | Mendoza, J.L.,Schneider, W.M.,Hoffmann, H.H.,Vercauteren, K.,Jude, K.M.,Xiong, A.,Moraga, I.,Horton, T.M.,Glenn, J.S.,de Jong, Y.P.,Rice, C.M.,Garcia, K.C. The IFN-lambda-IFN-lambda R1-IL-10R beta Complex Reveals Structural Features Underlying Type III IFN Functional Plasticity. Immunity, 46:379-392, 2017 Cited by PubMed: 28329704DOI: 10.1016/j.immuni.2017.02.017 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.847 Å) |
Structure validation
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