5SZ3
Carbonic anhydrase II in complex with 4-(3-quinolinyl)-benzenesulfonamide
Summary for 5SZ3
Entry DOI | 10.2210/pdb5sz3/pdb |
Related | 5SZ0 5SZ1 5SZ2 5SZ4 5SZ5 5SZ6 5SZ7 |
Descriptor | Carbonic anhydrase 2, ZINC ION, DIMETHYL SULFOXIDE, ... (5 entities in total) |
Functional Keywords | sulfonamide, inhibitor, zinc-binding, lyase-lyase inhibitor complex, lyase/lyase inhibitor |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm : P00918 |
Total number of polymer chains | 1 |
Total formula weight | 29673.05 |
Authors | Bhatt, A.,Mahon, B.P.,Cornelio, B.,McKenna, R. (deposition date: 2016-08-12, release date: 2016-12-21, Last modification date: 2023-10-04) |
Primary citation | Bhatt, A.,Mahon, B.P.,Cruzeiro, V.W.,Cornelio, B.,Laronze-Cochard, M.,Ceruso, M.,Sapi, J.,Rance, G.A.,Khlobystov, A.N.,Fontana, A.,Roitberg, A.,Supuran, C.T.,McKenna, R. Structure-Activity Relationships of Benzenesulfonamide-Based Inhibitors towards Carbonic Anhydrase Isoform Specificity. Chembiochem, 18:213-222, 2017 Cited by PubMed: 27860128DOI: 10.1002/cbic.201600513 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.689 Å) |
Structure validation
Download full validation report