5OLH
Structure of the A2A-StaR2-bRIL562-Vipadenant complex at 2.6A obtained from in meso soaking experiments.
Summary for 5OLH
Entry DOI | 10.2210/pdb5olh/pdb |
Descriptor | Adenosine receptor A2a,Soluble cytochrome b562,Adenosine receptor A2a, 3-[(4-azanyl-3-methyl-phenyl)methyl]-7-(furan-2-yl)-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine, OLEIC ACID, ... (7 entities in total) |
Functional Keywords | g-protein coupled receptor, adenosine 2a receptor, 7 tm integral membrane protein, thermostabilizing mutations, membrane protein |
Biological source | Homo sapiens (Human) More |
Cellular location | Cell membrane; Multi-pass membrane protein: P29274 |
Total number of polymer chains | 1 |
Total formula weight | 56661.35 |
Authors | Rucktooa, P.,Cheng, R.K.Y.,Segala, E.,Geng, T.,Errey, J.C.,Brown, G.A.,Cooke, R.,Marshall, F.H.,Dore, A.S. (deposition date: 2017-07-27, release date: 2018-01-17, Last modification date: 2024-01-17) |
Primary citation | Rucktooa, P.,Cheng, R.K.Y.,Segala, E.,Geng, T.,Errey, J.C.,Brown, G.A.,Cooke, R.M.,Marshall, F.H.,Dore, A.S. Towards high throughput GPCR crystallography: In Meso soaking of Adenosine A2A Receptor crystals. Sci Rep, 8:41-41, 2018 Cited by PubMed: 29311713DOI: 10.1038/s41598-017-18570-w PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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