5OJT
Structure-Activity Relationships and Biological Characterization of a Novel, Potent and Serum Stable C-X-C chemokine receptor type 4 (CXCR4) Antagonist
Summary for 5OJT
Entry DOI | 10.2210/pdb5ojt/pdb |
NMR Information | BMRB: 34165 |
Descriptor | ACE-ARG-ALA-(D)CYS-ARG-BNA-HIS-PEN (1 entity in total) |
Functional Keywords | cxcr4, peptide binding protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 999.24 |
Authors | Brancaccio, D.,Carotenuto, A. (deposition date: 2017-07-24, release date: 2017-11-22, Last modification date: 2023-11-15) |
Primary citation | Di Maro, S.,Di Leva, F.S.,Trotta, A.M.,Brancaccio, D.,Portella, L.,Aurilio, M.,Tomassi, S.,Messere, A.,Sementa, D.,Lastoria, S.,Carotenuto, A.,Novellino, E.,Scala, S.,Marinelli, L. Structure-Activity Relationships and Biological Characterization of a Novel, Potent, and Serum Stable C-X-C Chemokine Receptor Type 4 (CXCR4) Antagonist. J. Med. Chem., 60:9641-9652, 2017 Cited by PubMed: 29125295DOI: 10.1021/acs.jmedchem.7b01062 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
Download full validation report