5O97

Crystal structure of human BRD4(1) bromodomain in complex with JRMBR4106

Summary for 5O97

• Entry DOI: 10.2210/pdb5o97/pdb
• Descriptor: Bromodomain-containing protein 4, (5~{Z})-4-azanyl-5-[(3-methoxy-4-oxidanyl-phenyl)methylidene]-1,3-thiazol-2-one, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: brd4 bromodomain 1(brp4(1)), inhibitor, dna binding protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 15411.72

Authors

Zhu, J.,Marchand, J.R.,Caflisch, A. (deposition date: 2017-06-15, release date: 2018-06-27, Last modification date: 2024-01-17)

• Primary citation: Zhu, J.,Marchand, J.R.,Caflisch, A.; Crystal structure of human BRD4(1) bromodomain in complex with JRMBR4106; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.3 Å)