5O2U

Llama VHH in complex with p24

Summary for 5O2U

Entry DOI	10.2210/pdb5o2u/pdb
Descriptor	Capsid protein p24, VHH 59H10 (2 entities in total)
Functional Keywords	vhh llama antibody hiv capsid protein complex, virus
Biological source	Human immunodeficiency virus 1 (HIV-1) More
Cellular location	Gag polyprotein: Host cell membrane; Lipid- anchor . Matrix protein p17: Virion membrane; Lipid- anchor . Capsid protein p24: Virion . Nucleocapsid protein p7: Virion : P12493
Total number of polymer chains	4
Total formula weight	139684.40
Authors	Caillat, C.,Verrips, T.,Weissenhorn, W. (deposition date: 2017-05-22, release date: 2017-06-21, Last modification date: 2024-01-17)
Primary citation	Gray, E.R.,Brookes, J.C.,Caillat, C.,Turbe, V.,Webb, B.L.J.,Granger, L.A.,Miller, B.S.,McCoy, L.E.,El Khattabi, M.,Verrips, C.T.,Weiss, R.A.,Duffy, D.M.,Weissenhorn, W.,McKendry, R.A. Unravelling the Molecular Basis of High Affinity Nanobodies against HIV p24: In Vitro Functional, Structural, and in Silico Insights. ACS Infect Dis, 3:479-491, 2017 Cited by PubMed: 28591513 DOI: 10.1021/acsinfecdis.6b00189 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.76 Å)

Structure validation