5MRV
Crystal structure of human carboxypeptidase O in complex with NvCI
Summary for 5MRV
Entry DOI | 10.2210/pdb5mrv/pdb |
Descriptor | Carboxypeptidase O, Metallocarboxypeptidase inhibitor, ZINC ION, ... (5 entities in total) |
Functional Keywords | digestive metallocarboxypeptidase, food digestion, carboxypeptidase inhibitor, brush border enzyme, hydrolase |
Biological source | Homo sapiens (Human) More |
Cellular location | Apical cell membrane ; Lipid-anchor, GPI-anchor : Q8IVL8 |
Total number of polymer chains | 3 |
Total formula weight | 89009.27 |
Authors | Garcia-Pardo, J.,Garcia-Guerrero, M.C.,Fernandez-Alvarez, R.,Lyons, P.,Aviles, F.X.,Lorenzo, J.,Reverter, D. (deposition date: 2016-12-27, release date: 2018-01-17, Last modification date: 2024-01-17) |
Primary citation | Garcia-Guerrero, M.C.,Garcia-Pardo, J.,Berenguer, E.,Fernandez-Alvarez, R.,Barfi, G.B.,Lyons, P.J.,Aviles, F.X.,Huber, R.,Lorenzo, J.,Reverter, D. Crystal structure and mechanism of human carboxypeptidase O: Insights into its specific activity for acidic residues. Proc. Natl. Acad. Sci. U.S.A., 115:E3932-E3939, 2018 Cited by PubMed: 29636417DOI: 10.1073/pnas.1803685115 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.854 Å) |
Structure validation
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