5MI7
BtGH84 mutant with covalent modification by MA4 in complex with PUGNAc
Summary for 5MI7
Entry DOI | 10.2210/pdb5mi7/pdb |
Descriptor | O-GlcNAcase BT_4395, O-(2-ACETAMIDO-2-DEOXY D-GLUCOPYRANOSYLIDENE) AMINO-N-PHENYLCARBAMATE, ~{N}-(4-morpholin-4-ylthieno[2,3-d]pyrimidin-2-yl)propanamide, ... (5 entities in total) |
Functional Keywords | hydrolase, activator |
Biological source | Bacteroides thetaiotaomicron VPI-5482 |
Total number of polymer chains | 1 |
Total formula weight | 84287.21 |
Authors | Darby, J.F.,Davies, G.J.,Hubbard, R.E. (deposition date: 2016-11-27, release date: 2017-11-01, Last modification date: 2024-01-17) |
Primary citation | Darby, J.F.,Atobe, M.,Firth, J.D.,Bond, P.,Davies, G.J.,O'Brien, P.,Hubbard, R.E. Increase of enzyme activity through specific covalent modification with fragments. Chem Sci, 8:7772-7779, 2017 Cited by PubMed: 29163914DOI: 10.1039/c7sc01966a PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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