5MGQ
Solution structure of oxidized and amidated human IAPP (1-37), the diabetes II peptide.
Summary for 5MGQ
Entry DOI | 10.2210/pdb5mgq/pdb |
NMR Information | BMRB: 34069 |
Descriptor | Islet amyloid polypeptide (1 entity in total) |
Functional Keywords | recombinant human iapp, type ii diabetes, protein fibril |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 3908.32 |
Authors | Rodriguez Camargo, D.C.,Tripsianes, K.,Reif, B. (deposition date: 2016-11-21, release date: 2017-03-29, Last modification date: 2023-06-14) |
Primary citation | Rodriguez Camargo, D.C.,Tripsianes, K.,Buday, K.,Franko, A.,Gobl, C.,Hartlmuller, C.,Sarkar, R.,Aichler, M.,Mettenleiter, G.,Schulz, M.,Boddrich, A.,Erck, C.,Martens, H.,Walch, A.K.,Madl, T.,Wanker, E.E.,Conrad, M.,de Angelis, M.H.,Reif, B. The redox environment triggers conformational changes and aggregation of hIAPP in Type II Diabetes. Sci Rep, 7:44041-44041, 2017 Cited by PubMed: 28287098DOI: 10.1038/srep44041 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
Download full validation report