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5MGQ

Solution structure of oxidized and amidated human IAPP (1-37), the diabetes II peptide.

Functional Information from GO Data
ChainGOidnamespacecontents
A0005179molecular_functionhormone activity
A0005576cellular_componentextracellular region
Functional Information from PROSITE/UniProt
site_idPS00258
Number of Residues15
DetailsCALCITONIN Calcitonin / CGRP / IAPP family signature. CNT.ATCAtqrLanfL
ChainResidueDetails
ACYS2-LEU16

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues36
DetailsPeptide: {"description":"Islet amyloid polypeptide","featureId":"PRO_0000004106"}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues1
DetailsModified residue: {"description":"Tyrosine amide","evidences":[{"source":"PubMed","id":"2651160","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"3053705","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

240971

PDB entries from 2025-08-27

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