5LSC
The structure of the metallo-beta-lactamase VIM-2 in complex with a triazolylthioacetamide inhibitor
Summary for 5LSC
Entry DOI | 10.2210/pdb5lsc/pdb |
Descriptor | Metallo-beta-lactamase VIM-2-like protein, CHLORIDE ION, 2-[5-[2-(1,3-benzothiazol-2-ylamino)-2-oxidanylidene-ethyl]sulfanyl-4~{H}-1,2,4-triazol-3-yl]benzoic acid, ... (5 entities in total) |
Functional Keywords | antibiotic resistance, carbapenemases, verona integron-encoded metallo-beta-lactamase 2, vim-2, hydrolase |
Biological source | Pseudomonas aeruginosa |
Total number of polymer chains | 2 |
Total formula weight | 52506.73 |
Authors | Christopeit, T.,Yang, K.-W.,Yang, S.-K.,Leiros, H.-K.S. (deposition date: 2016-08-25, release date: 2016-11-09, Last modification date: 2024-01-17) |
Primary citation | Christopeit, T.,Yang, K.W.,Yang, S.K.,Leiros, H.K. The structure of the metallo-beta-lactamase VIM-2 in complex with a triazolylthioacetamide inhibitor. Acta Crystallogr F Struct Biol Commun, 72:813-819, 2016 Cited by PubMed: 27834790DOI: 10.1107/S2053230X16016113 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.497 Å) |
Structure validation
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