5LKJ

Crystal structure of mouse CARM1 in complex with ligand SA684

Summary for 5LKJ

• Entry DOI: 10.2210/pdb5lkj/pdb
• Descriptor: Histone-arginine methyltransferase CARM1, (2~{S})-4-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl-(2-carbamimidamidoethyl)amino]-2-azanyl-butanoic acid, 1,2-ETHANEDIOL, ... (7 entities in total)
• Functional Keywords: protein arginine methyltransferase, catalytic domain, chromatin regulator, mrna processing, mrna splicing, nucleus, s-adenosyl-l-methionine, transcription, transcription regulation, transferase
• Biological source: Mus musculus (House Mouse)
• Cellular location: Nucleus: Q9WVG6
• Total number of polymer chains: 4
• Total formula weight: 171344.31

Authors

Cura, V.,Marechal, N.,Mailliot, J.,Troffer-Charlier, N.,Hassenboehler, P.,Wurtz, J.M.,Bonnefond, L.,Cavarelli, J. (deposition date: 2016-07-22, release date: 2017-08-16, Last modification date: 2024-01-10)

• Primary citation: Cura, V.,Marechal, N.,Mailliot, J.,Troffer-Charlier, N.,Hassenboehler, P.,Wurtz, J.M.,Bonnefond, L.,Cavarelli, J.; Crystal structure of mouse CARM1 in complex with ligands; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.595 Å)