5LKJ
Crystal structure of mouse CARM1 in complex with ligand SA684
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Histone-arginine methyltransferase CARM1 | polymer | 371 | 41985.6 | 4 | UniProt (Q9WVG6) Pfam (PF06325) Pfam (PF22528) In PDB | Mus musculus (House Mouse) | Coactivator-associated arginine methyltransferase 1,Protein arginine N-methyltransferase 4 |
| 2 | A, B, C, D | (2~{S})-4-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl-(2-carbamimidamidoethyl)amino]-2-azanyl-butanoic acid | non-polymer | 452.5 | 4 | Chemie (6YB) | |||
| 3 | A, B, C | 1,2-ETHANEDIOL | non-polymer | 62.1 | 8 | Chemie (EDO) | |||
| 4 | A, B | 1,2-DIMETHOXYETHANE | non-polymer | 90.1 | 5 | Chemie (DXE) | |||
| 5 | A, C | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 3 | Chemie (PEG) | |||
| 6 | B | 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL | non-polymer | 326.4 | 1 | Chemie (P33) | |||
| 7 | water | water | 18.0 | 134 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 130 - 497 (UniProt: Q9WVG6)
| PDB | External Database | Details |
|---|---|---|
| Gly 127 | - | expression tag |
| His 128 | - | expression tag |
| Met 129 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 167942.5 | |
| Non-Polymers* | Number of molecules | 21 |
| Total formula weight | 3401.8 | |
| All* | Total formula weight | 171344.3 |
