5LFY
Zinc bound dimer of the fragment of human amyloid-beta peptide with Alzheimer's disease pathogenic Taiwanese mutation D7H
Summary for 5LFY
Entry DOI | 10.2210/pdb5lfy/pdb |
NMR Information | BMRB: 34019 |
Descriptor | Amyloid beta A4 protein, ZINC ION (2 entities in total) |
Functional Keywords | alzheimer's disease, amyloid-beta peptide, zinc complex, zinc-bound dimer, structural protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 2569.35 |
Authors | Polshakov, V.I.,Mantsyzov, A.B.,Kozin, S.A. (deposition date: 2016-07-05, release date: 2017-08-23, Last modification date: 2023-06-14) |
Primary citation | Polshakov, V.I.,Mantsyzov, A.B.,Kozin, S.A.,Adzhubei, A.A.,Zhokhov, S.S.,van Beek, W.,Kulikova, A.A.,Indeykina, M.I.,Mitkevich, V.A.,Makarov, A.A. A Binuclear Zinc Interaction Fold Discovered in the Homodimer of Alzheimer's Amyloid-beta Fragment with Taiwanese Mutation D7H. Angew. Chem. Int. Ed. Engl., 56:11734-11739, 2017 Cited by PubMed: 28570778DOI: 10.1002/anie.201704615 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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