5L2O
Crystal Structure of ALDH1A1 in complex with BUC22
Summary for 5L2O
Entry DOI | 10.2210/pdb5l2o/pdb |
Related | 5L13 5L2M 5L2N |
Descriptor | Retinal dehydrogenase 1, 7-(diethylamino)-4-methyl-2H-1-benzopyran-2-one, YTTERBIUM (III) ION, ... (5 entities in total) |
Functional Keywords | aldh1a1 inhibitor, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 8 |
Total formula weight | 442915.20 |
Authors | Buchman, C.D.,Hurley, T.D. (deposition date: 2016-08-02, release date: 2017-03-08, Last modification date: 2024-03-06) |
Primary citation | Buchman, C.D.,Hurley, T.D. Inhibition of the Aldehyde Dehydrogenase 1/2 Family by Psoralen and Coumarin Derivatives. J. Med. Chem., 60:2439-2455, 2017 Cited by PubMed: 28219011DOI: 10.1021/acs.jmedchem.6b01825 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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