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5L0A

Human muscle fructose-1,6-bisphosphatase E69Q mutant in active R-state in complex with fructose-1,6-bisphosphate

Summary for 5L0A
Entry DOI10.2210/pdb5l0a/pdb
Related3IFA 3IFC 4HE0 4HE1 4HE2 5ET5 5ET6 5ET7 5ET8
DescriptorFructose-1,6-bisphosphatase isozyme 2, 1,6-di-O-phosphono-beta-D-fructofuranose (3 entities in total)
Functional Keywordshydrolase, carbohydrate metabolism, glyconeogenesis, muscle izoenzyme, fbpase, r-state, leucine lock, e69q, fructose-1, 6-bisphosphate
Biological sourceHomo sapiens (Human)
Cellular locationCell junction : O00757
Total number of polymer chains1
Total formula weight37006.03
Authors
Barciszewski, J.,Wisniewski, J.,Kolodziejczyk, R.,Dzugaj, A.,Jaskolski, M.,Rakus, D. (deposition date: 2016-07-27, release date: 2017-08-16, Last modification date: 2024-01-10)
Primary citationBarciszewski, J.,Szpotkowski, K.,Wisniewski, J.,Kolodziejczyk, R.,Jaskolski, M.,Rakus, D.,Dzugaj, A.
Structural studies of human muscle FBPase
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.302 Å)
Structure validation

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