5K9V
Protein Tyrosine Phosphatase 1B (1-301), open state
Summary for 5K9V
| Entry DOI | 10.2210/pdb5k9v/pdb |
| Related | 5K9W 5KA0 5KA1 5KA2 5KA3 5KA4 5KA7 5KA8 5KA9 5KAA 5KAB 5KAC 5KAD |
| Descriptor | Tyrosine-protein phosphatase non-receptor type 1, CHLORIDE ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (5 entities in total) |
| Functional Keywords | protein tyrosine phosphatase, hydrolase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 36099.00 |
| Authors | Choy, M.S.,Peti, W.,Page, R. (deposition date: 2016-06-01, release date: 2017-03-01, Last modification date: 2023-09-27) |
| Primary citation | Choy, M.S.,Li, Y.,Machado, L.E.,Kunze, M.B.,Connors, C.R.,Wei, X.,Lindorff-Larsen, K.,Page, R.,Peti, W. Conformational Rigidity and Protein Dynamics at Distinct Timescales Regulate PTP1B Activity and Allostery. Mol. Cell, 65:644-658.e5, 2017 Cited by PubMed: 28212750DOI: 10.1016/j.molcel.2017.01.014 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.898 Å) |
Structure validation
Download full validation report
