5K8P
Zn2+/Tetrahedral intermediate-bound R289A 5-nitroanthranilate aminohydrolase
Summary for 5K8P
Entry DOI | 10.2210/pdb5k8p/pdb |
Related | 5K8M 5K8N 5K8O |
Descriptor | 5-nitroanthranilic acid aminohydrolase, ZINC ION, (6~{R})-6-azanyl-3-nitro-6-oxidanyl-cyclohexa-1,3-diene-1-carboxylic acid, ... (5 entities in total) |
Functional Keywords | nitroaromatics, deaminase, metalloenzyme, hydrolase |
Biological source | Bradyrhizobium sp. |
Total number of polymer chains | 8 |
Total formula weight | 372976.42 |
Authors | Kalyoncu, S. (deposition date: 2016-05-30, release date: 2016-10-05, Last modification date: 2023-09-27) |
Primary citation | Kalyoncu, S.,Heaner, D.P.,Kurt, Z.,Bethel, C.M.,Ukachukwu, C.U.,Chakravarthy, S.,Spain, J.C.,Lieberman, R.L. Enzymatic hydrolysis by transition-metal-dependent nucleophilic aromatic substitution. Nat.Chem.Biol., 12:1031-1036, 2016 Cited by PubMed: 27694799DOI: 10.1038/nchembio.2191 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)