5K47
CryoEM structure of the human Polycystin-2/PKD2 TRP channel
Summary for 5K47
Entry DOI | 10.2210/pdb5k47/pdb |
EMDB information | 8200 |
Descriptor | Polycystin-2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total) |
Functional Keywords | ion channel, transient receptor potential channel, polycystic kidney disease, structural genomics, structural genomics consortium, sgc, transport protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 259413.94 |
Authors | Pike, A.C.W.,Grieben, M.,Shintre, C.A.,Tessitore, A.,Shrestha, L.,Mukhopadhyay, S.,Mahajan, P.,Chalk, R.,Burgess-Brown, N.A.,Huiskonen, J.T.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Carpenter, E.P.,Structural Genomics Consortium (SGC) (deposition date: 2016-05-20, release date: 2016-08-24, Last modification date: 2020-10-21) |
Primary citation | Grieben, M.,Pike, A.C.,Shintre, C.A.,Venturi, E.,El-Ajouz, S.,Tessitore, A.,Shrestha, L.,Mukhopadhyay, S.,Mahajan, P.,Chalk, R.,Burgess-Brown, N.A.,Sitsapesan, R.,Huiskonen, J.T.,Carpenter, E.P. Structure of the polycystic kidney disease TRP channel Polycystin-2 (PC2). Nat. Struct. Mol. Biol., 24:114-122, 2017 Cited by PubMed: 27991905DOI: 10.1038/nsmb.3343 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.2 Å) |
Structure validation
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