5JNX
The 6.6 A cryo-EM structure of the full-length human NPC1 in complex with the cleaved glycoprotein of Ebola virus
Summary for 5JNX
Entry DOI | 10.2210/pdb5jnx/pdb |
Related | 3JD8 |
EMDB information | 8169 |
Descriptor | Niemann-Pick C1 protein, Envelope glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
Functional Keywords | protein complex, membrane protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 7 |
Total formula weight | 244801.86 |
Authors | Gong, X.,Qian, H.W.,Zhou, X.H.,Wu, J.P.,Wan, T.,Shi, Y.,Gao, F.,Zhou, Q.,Yan, N. (deposition date: 2016-05-01, release date: 2016-06-15, Last modification date: 2020-08-05) |
Primary citation | Gong, X.,Qian, H.,Zhou, X.,Wu, J.,Wan, T.,Cao, P.,Huang, W.,Zhao, X.,Wang, X.,Wang, P.,Shi, Y.,Gao, G.F.,Zhou, Q.,Yan, N. Structural Insights into the Niemann-Pick C1 (NPC1)-Mediated Cholesterol Transfer and Ebola Infection Cell, 165:1467-1478, 2016 Cited by PubMed: 27238017DOI: 10.1016/j.cell.2016.05.022 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (6.56 Å) |
Structure validation
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