5J5D

Crystal structure of Dihydrodipicolinate Synthase from Mycobacterium tuberculosis in complex with alpha-ketopimelic acid

Summary for 5J5D

Entry DOI	10.2210/pdb5j5d/pdb
Descriptor	4-hydroxy-tetrahydrodipicolinate synthase, SODIUM ION, 2-oxoheptanedioic acid, ... (4 entities in total)
Functional Keywords	dap pathway, l-lysine, alpha-ketopimelic acid, lyase
Biological source	Mycobacterium tuberculosis H37Rv
Cellular location	Cytoplasm : P9WP25
Total number of polymer chains	1
Total formula weight	31108.35
Authors	Navratna, V.,Gopal, B. (deposition date: 2016-04-02, release date: 2016-08-17, Last modification date: 2023-11-08)
Primary citation	Shrivastava, P.,Navratna, V.,Silla, Y.,Dewangan, R.P.,Pramanik, A.,Chaudhary, S.,Rayasam, G.,Kumar, A.,Gopal, B.,Ramachandran, S. Inhibition of Mycobacterium tuberculosis dihydrodipicolinate synthase by alpha-ketopimelic acid and its other structural analogues Sci Rep, 6:30827-30827, 2016 Cited by PubMed: 27501775 DOI: 10.1038/srep30827 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation