5J0O

Binary complex crystal structure of DNA polymerase Beta with A:A mismatch at the primer terminus

Summary for 5J0O

• Entry DOI: 10.2210/pdb5j0o/pdb
• Related: 5J0P 5J0Q 5J0R 5J0S 5J0T 5J0U 5J0V 5J0W 5J0X 5J0Y 5J29 5J2A 5J2B 5J2C 5J2D 5J2E 5J2F 5J2G 5J2H 5J2I 5J2J 5J2K
• Descriptor: DNA polymerase beta, DNA (5'-D(*CP*CP*GP*AP*CP*AP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ... (6 entities in total)
• Functional Keywords: dna polymerase beta, mismatch extension, binary complex, transferase-dna complex, transferase/dna
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus: P06746
• Total number of polymer chains: 4
• Total formula weight: 47745.88

Authors

Batra, V.K.,Wilson, S.H. (deposition date: 2016-03-28, release date: 2016-10-26, Last modification date: 2023-09-27)

• Primary citation: Batra, V.K.,Beard, W.A.,Pedersen, L.C.,Wilson, S.H.; Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism.; Structure, 24:1863-1875, 2016; PubMed: 27642161; DOI: 10.1016/j.str.2016.08.006

Experimental method

X-RAY DIFFRACTION (2 Å)