5HTI
Crystal structure of c-Met kinase domain in complex with LXM108
Summary for 5HTI
Entry DOI | 10.2210/pdb5hti/pdb |
Descriptor | Hepatocyte growth factor receptor, N-[3-fluoro-4-({7-[2-(morpholin-4-yl)ethoxy]-1,6-naphthyridin-4-yl}oxy)phenyl]-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide (3 entities in total) |
Functional Keywords | c-met inhibitor, transferase |
Biological source | Homo sapiens (Human) |
Cellular location | Membrane; Single-pass type I membrane protein. Isoform 3: Secreted: P08581 |
Total number of polymer chains | 1 |
Total formula weight | 36623.18 |
Authors | |
Primary citation | Xu, Y.C.,Long, Y. Crystal structure of c-Met kinase domain in complex with LXM108 to be published, |
Experimental method | X-RAY DIFFRACTION (1.66 Å) |
Structure validation
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