5HCE
Ternary complex of human Complement C5 with Ornithodoros moubata OmCI and Rhipicephalus appendiculatus RaCI1
Summary for 5HCE
Entry DOI | 10.2210/pdb5hce/pdb |
Descriptor | Complement C5, Complement inhibitor, Rhipicephalus appendiculatus RaCI1, ... (6 entities in total) |
Functional Keywords | complement, inflammation, inhibitor, tick, immune system |
Biological source | Ornithodoros moubata (Soft tick) More |
Total number of polymer chains | 4 |
Total formula weight | 213822.45 |
Authors | Jore, M.M.,Johnson, S.,Lea, S.M. (deposition date: 2016-01-04, release date: 2016-03-30, Last modification date: 2024-01-10) |
Primary citation | Jore, M.M.,Johnson, S.,Sheppard, D.,Barber, N.M.,Li, Y.I.,Nunn, M.A.,Elmlund, H.,Lea, S.M. Structural basis for therapeutic inhibition of complement C5. Nat.Struct.Mol.Biol., 23:378-386, 2016 Cited by PubMed: 27018802DOI: 10.1038/nsmb.3196 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.12 Å) |
Structure validation
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