5H9N

Crystal structure of LTBP1 Y114A mutant in complex with leukotriene C4

Summary for 5H9N

• Entry DOI: 10.2210/pdb5h9n/pdb
• Related: 5H9L 5HA0 5HAE
• Descriptor: Lipocalin AI-4, (5~{S},6~{R},7~{E},9~{E},11~{Z},14~{Z})-6-[(2~{R})-2-[[(4~{S})-4-azanyl-5-oxidanyl-5-oxidanylidene-pentanoyl]amino]-3-(2-hydroxy-2-oxoethylamino)-3-oxidanylidene-propyl]sulfanyl-5-oxidanyl-icosa-7,9,11,14-tetraenoic acid (3 entities in total)
• Functional Keywords: lipocalin, rhodnius, salivary, transport protein
• Biological source: Rhodnius prolixus (Triatomid bug)
• Total number of polymer chains: 1
• Total formula weight: 17438.39

Authors

Andersen, J.F. (deposition date: 2015-12-28, release date: 2016-05-11, Last modification date: 2017-05-24)

• Primary citation: Jablonka, W.,Pham, V.,Nardone, G.,Gittis, A.,Silva-Cardoso, L.,Atella, G.C.,Ribeiro, J.M.,Andersen, J.F.; Structure and Ligand-Binding Mechanism of a Cysteinyl Leukotriene-Binding Protein from a Blood-Feeding Disease Vector.; Acs Chem.Biol., 11:1934-1944, 2016; PubMed: 27124118; DOI: 10.1021/acschembio.6b00032

Experimental method

X-RAY DIFFRACTION (1.28 Å)