5F4T

Crystal structure of the human sperm Izumo1 residues 22-254

Summary for 5F4T

Entry DOI	10.2210/pdb5f4t/pdb
Related	5F4E 5F4Q 5F4V
Descriptor	Izumo sperm-egg fusion protein 1, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
Functional Keywords	glycoprotein, membrane-bound, cysteine-rich, adhesion, fusion, cell adhesion
Biological source	Homo sapiens (Human)
Cellular location	Membrane ; Single-pass type I membrane protein : Q8IYV9
Total number of polymer chains	1
Total formula weight	27402.45
Authors	Aydin, H.,Sultana, A.,Lee, J.E. (deposition date: 2015-12-03, release date: 2016-06-15, Last modification date: 2023-09-27)
Primary citation	Aydin, H.,Sultana, A.,Li, S.,Thavalingam, A.,Lee, J.E. Molecular architecture of the human sperm IZUMO1 and egg JUNO fertilization complex. Nature, 534:562-565, 2016 Cited by PubMed: 27309818 DOI: 10.1038/nature18595 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.083 Å)

Structure validation