5F2B
Expanding Nature's Catalytic Repertoire -Directed Evolution of an Artificial Metalloenzyme for In Vivo Metathesis
Summary for 5F2B
Entry DOI | 10.2210/pdb5f2b/pdb |
Descriptor | Streptavidin, [1-[4-[[5-[(3~{a}~{S},4~{S},6~{a}~{R})-2-oxidanylidene-1,3,3~{a},4,6,6~{a}-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]methyl]-2,6-dimethyl-phenyl]-3-(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-1-ium-2-yl]-bis(chloranyl)ruthenium, SULFATE ION, ... (4 entities in total) |
Functional Keywords | biotin-binding protein, beta barrel, metathesis, organometallic complex |
Biological source | Streptomyces avidinii |
Cellular location | Secreted: P22629 |
Total number of polymer chains | 1 |
Total formula weight | 17413.85 |
Authors | Heinisch, T.,Jeschek, M.,Reuter, R.,Trindler, C.,Panke, S.,Ward, T.R. (deposition date: 2015-12-01, release date: 2016-08-31, Last modification date: 2024-01-10) |
Primary citation | Jeschek, M.,Reuter, R.,Heinisch, T.,Trindler, C.,Klehr, J.,Panke, S.,Ward, T.R. Directed evolution of artificial metalloenzymes for in vivo metathesis. Nature, 537:661-665, 2016 Cited by PubMed: 27571282DOI: 10.1038/nature19114 PDB entries with the same primary citation |
Experimental method |
Structure validation
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