5EXW

Crystal structure of human GRP78 (70kDa heat shock protein 5 / BIP) ATPase domain in complex with 7-deaza-ATP

Summary for 5EXW

• Entry DOI: 10.2210/pdb5exw/pdb
• Related: 5EVZ 5EX5 5EY4 5F0X 5F1X 5F2R
• Descriptor: 78 kDa glucose-regulated protein, 7-deazaadenosine-5'-triphosphate (3 entities in total)
• Functional Keywords: chaperone, atpase domain, nucleotide-binding, endoplasmic reticulum
• Biological source: Homo sapiens (Human)
• Cellular location: Endoplasmic reticulum lumen: P11021
• Total number of polymer chains: 2
• Total formula weight: 89724.57

Authors

Hughes, S.J.,Antoshchenko, T.,Song, J.H.,Pizarro, J.,Park, H.W. (deposition date: 2015-11-24, release date: 2016-06-15, Last modification date: 2023-09-27)

• Primary citation: Hughes, S.J.,Antoshchenko, T.,Chen, Y.,Lu, H.,Pizarro, J.C.,Park, H.W.; Probing the ATP Site of GRP78 with Nucleotide Triphosphate Analogs.; Plos One, 11:e0154862-e0154862, 2016; PubMed: 27144892; DOI: 10.1371/journal.pone.0154862

Experimental method

X-RAY DIFFRACTION (1.9 Å)