5EXW
Crystal structure of human GRP78 (70kDa heat shock protein 5 / BIP) ATPase domain in complex with 7-deaza-ATP
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | 78 kDa glucose-regulated protein | polymer | 400 | 44356.1 | 2 | UniProt (P11021) Pfam (PF00012) In PDB | Homo sapiens (Human) | GRP-78, Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78, Heat shock 70 kDa protein 5, Immunoglobulin heavy chain-binding protein, BiP |
2 | A, B | 7-deazaadenosine-5'-triphosphate | non-polymer | 506.2 | 2 | Chemie (7DT) | |||
3 | water | water | 18.0 | 653 | Chemie (HOH) |
Sequence modifications
A, B: 26 - 407 (UniProt: P11021)
PDB | External Database | Details |
---|---|---|
Met 8 | - | expression tag |
His 9 | - | expression tag |
His 10 | - | expression tag |
His 11 | - | expression tag |
His 12 | - | expression tag |
His 13 | - | expression tag |
His 14 | - | expression tag |
Ser 15 | - | expression tag |
Ser 16 | - | expression tag |
Gly 17 | - | expression tag |
Arg 18 | - | expression tag |
Glu 19 | - | expression tag |
Asn 20 | - | expression tag |
Leu 21 | - | expression tag |
Tyr 22 | - | expression tag |
Phe 23 | - | expression tag |
Gln 24 | - | expression tag |
Gly 25 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 88712.2 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 1012.4 | |
All* | Total formula weight | 89724.6 |