5EXK
Crystal structure of M. tuberculosis lipoyl synthase with 6-thiooctanoyl peptide intermediate
Summary for 5EXK
Entry DOI | 10.2210/pdb5exk/pdb |
Related | 5EXI 5EXJ |
Descriptor | Lipoyl synthase, Octanoylated peptide from M. tuberculosis H protein, FE3-S4 CLUSTER, ... (10 entities in total) |
Functional Keywords | auxiliary iron-sulfur cluster, adomet radical, radical sam, sulfur insertion, transferase |
Biological source | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) More |
Total number of polymer chains | 12 |
Total formula weight | 234256.65 |
Authors | McLaughlin, M.I.,Lanz, N.D.,Goldman, P.J.,Lee, K.-H.,Booker, S.J.,Drennan, C.L. (deposition date: 2015-11-23, release date: 2016-08-10, Last modification date: 2019-11-27) |
Primary citation | McLaughlin, M.I.,Lanz, N.D.,Goldman, P.J.,Lee, K.H.,Booker, S.J.,Drennan, C.L. Crystallographic snapshots of sulfur insertion by lipoyl synthase. Proc.Natl.Acad.Sci.USA, 113:9446-9450, 2016 Cited by PubMed: 27506792DOI: 10.1073/pnas.1602486113 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.86 Å) |
Structure validation
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