5E95

Crystal Structure of Mb(NS1)/H-Ras Complex

Summary for 5E95

• Entry DOI: 10.2210/pdb5e95/pdb
• Descriptor: Mb(NS1), GTPase HRas, GUANOSINE-5'-DIPHOSPHATE, ... (5 entities in total)
• Functional Keywords: h-ras, monobody, inhibitor, complex, signaling protein-inhibitor complex, signaling protein/inhibitor
• Biological source: Homo sapiens; More
• Total number of polymer chains: 2
• Total formula weight: 29907.47

Authors

Eguchi, R.R.,Sha, F.,Gupta, A.,Koide, A.,Koide, S. (deposition date: 2015-10-14, release date: 2016-11-02, Last modification date: 2023-09-27)

• Primary citation: Spencer-Smith, R.,Koide, A.,Zhou, Y.,Eguchi, R.R.,Sha, F.,Gajwani, P.,Santana, D.,Gupta, A.,Jacobs, M.,Herrero-Garcia, E.,Cobbert, J.,Lavoie, H.,Smith, M.,Rajakulendran, T.,Dowdell, E.,Okur, M.N.,Dementieva, I.,Sicheri, F.,Therrien, M.,Hancock, J.F.,Ikura, M.,Koide, S.,O'Bryan, J.P.; Inhibition of RAS function through targeting an allosteric regulatory site.; Nat. Chem. Biol., 13:62-68, 2017; PubMed: 27820802; DOI: 10.1038/nchembio.2231

Experimental method

X-RAY DIFFRACTION (1.402 Å)