6U7T
MutY adenine glycosylase bound to DNA containing a transition state analog (1N) paired with d(8-oxo-G)
Replaces: 5DPKReplaces: 3FSQSummary for 6U7T
Entry DOI | 10.2210/pdb6u7t/pdb |
Related | 6Q0C |
Descriptor | Adenine DNA glycosylase, DNA (5'-D(*AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3'), DNA (5'-D(P*GP*TP*CP*CP*AP*(NR1)P*GP*TP*CP*T)-3'), ... (6 entities in total) |
Functional Keywords | protein-dna complex, dna repair, transition state analog, hydrolase-dna complex, hydrolase, hydrolase/dna |
Biological source | Geobacillus stearothermophilus More |
Total number of polymer chains | 3 |
Total formula weight | 48856.77 |
Authors | O'Shea Murray, V.L.,Cao, S.,Horvath, M.P.,David, S.S. (deposition date: 2019-09-03, release date: 2019-10-02, Last modification date: 2023-10-11) |
Primary citation | Russelburg, L.P.,O'Shea Murray, V.L.,Demir, M.,Knutsen, K.R.,Sehgal, S.L.,Cao, S.,David, S.S.,Horvath, M.P. Structural Basis for Finding OG Lesions and Avoiding Undamaged G by the DNA Glycosylase MutY. Acs Chem.Biol., 15:93-102, 2020 Cited by PubMed: 31829624DOI: 10.1021/acschembio.9b00639 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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