6U7T
MutY adenine glycosylase bound to DNA containing a transition state analog (1N) paired with d(8-oxo-G)
Replaces: 5DPKReplaces: 3FSQEntity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Adenine DNA glycosylase | polymer | 366 | 41810.6 | 1 | UniProt (P83847) Pfam (PF00730) Pfam (PF00633) Pfam (PF10576) Pfam (PF14815) In PDB | Geobacillus stearothermophilus | oxoG:A-specific adenine glycosylase |
| 2 | B | DNA (5'-D(*AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3') | polymer | 11 | 3423.2 | 1 | synthetic construct | ||
| 3 | C | DNA (5'-D(P*GP*TP*CP*CP*AP*(NR1)P*GP*TP*CP*T)-3') | polymer | 11 | 3191.1 | 1 | synthetic construct | ||
| 4 | A | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 1 | Chemie (SF4) | |||
| 5 | A | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 6 | water | water | 18.0 | 75 | Chemie (HOH) |
Sequence modifications
A: 1 - 366 (UniProt: P83847)
| PDB | External Database | Details |
|---|---|---|
| Pro 364 | Arg 364 | variant |
| Pro 366 | Asp 366 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 48425.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 431.8 | |
| All* | Total formula weight | 48856.8 |
