5DFJ
Human APE1 E96Q/D210N mismatch substrate complex
Summary for 5DFJ
Entry DOI | 10.2210/pdb5dfj/pdb |
Related | 5DFF 5DFH 5DFI |
Descriptor | DNA-(apurinic or apyrimidinic site) lyase, DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*TP*(3DR)P*CP*GP*AP*CP*GP*GP*AP*TP*CP*C)-3'), DNA (5'-D(*GP*GP*AP*TP*CP*CP*GP*TP*CP*GP*GP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... (6 entities in total) |
Functional Keywords | hydrolase, lyase/dna, lyase-dna complex |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus. DNA-(apurinic or apyrimidinic site) lyase, mitochondrial: Mitochondrion: P27695 |
Total number of polymer chains | 4 |
Total formula weight | 75577.11 |
Authors | Freudenthal, B.D.,Wilson, S.H. (deposition date: 2015-08-26, release date: 2015-10-14, Last modification date: 2024-03-13) |
Primary citation | Freudenthal, B.D.,Beard, W.A.,Cuneo, M.J.,Dyrkheeva, N.S.,Wilson, S.H. Capturing snapshots of APE1 processing DNA damage. Nat.Struct.Mol.Biol., 22:924-931, 2015 Cited by PubMed: 26458045DOI: 10.1038/nsmb.3105 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
Download full validation report