5D5M
Structure of human MR1-5-OP-RU in complex with human MAIT M33.64 TCR
Summary for 5D5M
Entry DOI | 10.2210/pdb5d5m/pdb |
Descriptor | Major histocompatibility complex class I-related gene protein, Beta-2-microglobulin, M33.64 TCR Alpha Chain, ... (8 entities in total) |
Functional Keywords | antigen, immune system |
Biological source | Homo sapiens (Human) More |
Cellular location | Cell membrane; Single-pass membrane protein; Extracellular side. Isoform 4: Secreted. Isoform 3: Cell membrane ; Single-pass type I membrane protein : Q95460 Secreted : P61769 |
Total number of polymer chains | 8 |
Total formula weight | 188232.22 |
Authors | Keller, A.N.,Birkinshaw, R.W.,Rossjohn, J. (deposition date: 2015-08-11, release date: 2016-01-27, Last modification date: 2023-09-27) |
Primary citation | Gherardin, N.A.,Keller, A.N.,Woolley, R.E.,Le Nours, J.,Ritchie, D.S.,Neeson, P.J.,Birkinshaw, R.W.,Eckle, S.B.,Waddington, J.N.,Liu, L.,Fairlie, D.P.,Uldrich, A.P.,Pellicci, D.G.,McCluskey, J.,Godfrey, D.I.,Rossjohn, J. Diversity of T Cells Restricted by the MHC Class I-Related Molecule MR1 Facilitates Differential Antigen Recognition. Immunity, 44:32-45, 2016 Cited by PubMed: 26795251DOI: 10.1016/j.immuni.2015.12.005 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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