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5CSJ

S100B-RSK1 crystal structure B

Summary for 5CSJ
Entry DOI10.2210/pdb5csj/pdb
DescriptorProtein S100-B, Ribosomal protein S6 kinase alpha-1, CALCIUM ION, ... (5 entities in total)
Functional Keywordskinase, s100, inhibitor, signaling, transferase
Biological sourceHomo sapiens (Human)
More
Cellular locationCytoplasm : P04271
Nucleus: Q15418
Total number of polymer chains3
Total formula weight26648.52
Authors
Gogl, G.,Nyitray, L. (deposition date: 2015-07-23, release date: 2015-11-11, Last modification date: 2024-01-10)
Primary citationGogl, G.,Alexa, A.,Kiss, B.,Katona, G.,Kovacs, M.,Bodor, A.,Remenyi, A.,Nyitray, L.
Structural Basis of Ribosomal S6 Kinase 1 (RSK1) Inhibition by S100B Protein: MODULATION OF THE EXTRACELLULAR SIGNAL-REGULATED KINASE (ERK) SIGNALING CASCADE IN A CALCIUM-DEPENDENT WAY.
J.Biol.Chem., 291:11-27, 2016
Cited by
PubMed: 26527685
DOI: 10.1074/jbc.M115.684928
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.7 Å)
Structure validation

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