5CBA
3B4 in complex with CXCL13 - 3B4-CXCL13
Summary for 5CBA
Entry DOI | 10.2210/pdb5cba/pdb |
Related | 5C2B |
Descriptor | 3b4 heavy chain, 3b4 light chain, C-X-C motif chemokine 13, ... (6 entities in total) |
Functional Keywords | anti-cxcl13, cxcl13, scfv, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 75774.83 |
Authors | Tu, C.,Bard, J.,Mosyak, L. (deposition date: 2015-06-30, release date: 2015-11-04, Last modification date: 2023-09-27) |
Primary citation | Tu, C.,Terraube, V.,Tam, A.S.,Stochaj, W.,Fennell, B.J.,Lin, L.,Stahl, M.,LaVallie, E.R.,Somers, W.,Finlay, W.J.,Mosyak, L.,Bard, J.,Cunningham, O. A Combination of Structural and Empirical Analyses Delineates the Key Contacts Mediating Stability and Affinity Increases in an Optimized Biotherapeutic Single-chain Fv (scFv). J. Biol. Chem., 291:1267-1276, 2016 Cited by PubMed: 26515064DOI: 10.1074/jbc.M115.688010 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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