6JBG

Crystal structure of the bacterial ribosomal decoding site in complex with 4'-deoxy-4'-fluoro neamine analog (equatorial 4'-F)

Replaces:  5BXK

Summary for 6JBG

• Entry DOI: 10.2210/pdb6jbg/pdb
• Descriptor: RNA (5'-R(P*UP*GP*CP*GP*UP*CP*AP*CP*GP*CP*CP*GP*GP*CP*GP*AP*AP*GP*UP*CP*GP*C)-3'), RNA (5'-R(*UP*UP*GP*CP*GP*UP*CP*AP*CP*GP*CP*CP*GP*GP*CP*GP*AP*AP*GP*UP*CP*GP*C)-3'), (1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl 2,6-diamino-2,4,6-trideoxy-4-fluoro-alpha-D-glucopyranoside, ... (4 entities in total)
• Functional Keywords: rna, antibiotic, rna-antibiotic complex, rna/antibiotic
• Biological source: synthetic construct; More
• Total number of polymer chains: 4
• Total formula weight: 29193.71

Authors

Kanazawa, H.,Auffinger, P.,Hanessian, S.,Kondo, J. (deposition date: 2019-01-25, release date: 2020-01-29, Last modification date: 2023-11-22)

• Primary citation: Kondo, J.,Hanessian, S.,Kanazawa, H.; Crystal structure of the bacterial ribosomal decoding site in complex with 4'-deoxy-4'-fluoro neamine analog (axial 4'-F); To Be Published,

Experimental method

X-RAY DIFFRACTION (3.1 Å)