5BRX
X-ray crystal structure of Aplysia californica (Ac-AChBP) in complex with 2-pyridyl azatricyclo[3.3.1.13,7]decane; 2-pyridylazaadamantane; 2-Aza (TI-8480)
Summary for 5BRX
Entry DOI | 10.2210/pdb5brx/pdb |
Descriptor | Soluble acetylcholine receptor, SULFATE ION, (2R,3S,5R,7S)-2-(pyridin-3-yl)-1-azatricyclo[3.3.1.1~3,7~]decane, ... (5 entities in total) |
Functional Keywords | achbp, nicotine, acetylcholine, acetylcholine binding protein |
Biological source | Aplysia californica (California sea hare) |
Total number of polymer chains | 10 |
Total formula weight | 265334.62 |
Authors | Bobango, J.,Sankaran, B.,Park, J.F.,Wu, J.,Talley, T.T. (deposition date: 2015-06-01, release date: 2015-06-24, Last modification date: 2023-09-27) |
Primary citation | Bobango, J.,Sankaran, B.,Park, J.F.,Wu, J.,Talley, T.T. Comparisons of Binding Affinities for Neuronal Nicotinic Receptors (NNRs) and AChBPs To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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