5BQN
Crystal structure of the LHn fragment of botulinum neurotoxin type D, mutant H233Y E230Q
Summary for 5BQN
Entry DOI | 10.2210/pdb5bqn/pdb |
Descriptor | Botulinum neurotoxin type D,Botulinum neurotoxin type D, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID (3 entities in total) |
Functional Keywords | botulinum neurotoxin, targeted secretion inhibitors, endopeptidase, type d, protein engineering, hydrolase |
Biological source | Clostridium botulinum More |
Cellular location | Botulinum neurotoxin D light chain: Secreted. Botulinum neurotoxin D heavy chain: Secreted: P19321 |
Total number of polymer chains | 1 |
Total formula weight | 102093.90 |
Authors | Masuyer, G.,Davies, J.R.,Moore, K.,Chaddock, J.A.,Acharya, K.R. (deposition date: 2015-05-29, release date: 2015-08-19, Last modification date: 2024-01-10) |
Primary citation | Masuyer, G.,Davies, J.R.,Moore, K.,Chaddock, J.A.,Ravi Acharya, K. Structural analysis of Clostridium botulinum neurotoxin type D as a platform for the development of targeted secretion inhibitors. Sci Rep, 5:13397-13397, 2015 Cited by PubMed: 26324071DOI: 10.1038/srep13397 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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