5BOM
DNA polymerase beta binary complex with a templating 5ClC
Summary for 5BOM
Entry DOI | 10.2210/pdb5bom/pdb |
Descriptor | DNA polymerase beta, DNA (5'-D(P*GP*TP*CP*GP*G)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), ... (6 entities in total) |
Functional Keywords | transferase, lyase/dna, lyase-dna complex |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 47771.26 |
Authors | Freudenthal, B.D.,Wilson, S.H. (deposition date: 2015-05-27, release date: 2015-08-19, Last modification date: 2023-09-27) |
Primary citation | Fedeles, B.I.,Freudenthal, B.D.,Yau, E.,Singh, V.,Chang, S.C.,Li, D.,Delaney, J.C.,Wilson, S.H.,Essigmann, J.M. Intrinsic mutagenic properties of 5-chlorocytosine: A mechanistic connection between chronic inflammation and cancer. Proc.Natl.Acad.Sci.USA, 112:E4571-E4580, 2015 Cited by PubMed: 26243878DOI: 10.1073/pnas.1507709112 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.0002 Å) |
Structure validation
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