5BOJ
Crystal Structure of Human Transthyretin in Complex with Gemfibrozil
Summary for 5BOJ
Entry DOI | 10.2210/pdb5boj/pdb |
Related | 4qxv |
Descriptor | Transthyretin, 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid, SODIUM ION, ... (4 entities in total) |
Functional Keywords | transport protein, thyroxine binding, gemfibrozil complex |
Biological source | Homo sapiens (Human) |
Cellular location | Secreted: P02766 |
Total number of polymer chains | 2 |
Total formula weight | 28078.38 |
Authors | Begum, A.,Olofsson, A.,Sauer-Eriksson, A.E. (deposition date: 2015-05-27, release date: 2015-08-05, Last modification date: 2024-01-10) |
Primary citation | Iakovleva, I.,Brannstrom, K.,Nilsson, L.,Gharibyan, A.L.,Begum, A.,Anan, I.,Walfridsson, M.,Sauer-Eriksson, A.E.,Olofsson, A. Enthalpic Forces Correlate with the Selectivity of Transthyretin-Stabilizing Ligands in Human Plasma. J.Med.Chem., 58:6507-6515, 2015 Cited by PubMed: 26214366DOI: 10.1021/acs.jmedchem.5b00544 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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