5BOC
Crystal structure of topoisomerase ParE inhibitor
Summary for 5BOC
Entry DOI | 10.2210/pdb5boc/pdb |
Related | 5BOD |
Descriptor | DNA topoisomerase 4 subunit B, 3-methyl-4-({3-[3-methyl-5-(trifluoromethyl)phenyl]-1H-pyrazol-5-yl}carbamoyl)benzoic acid (3 entities in total) |
Functional Keywords | inhibitor, complex, topoisomerase, pare, isomerase-isomerase inhibitor complex, isomerase/isomerase inhibitor |
Biological source | Streptococcus pneumoniae R6 |
Total number of polymer chains | 1 |
Total formula weight | 25004.08 |
Authors | Tan, Y.W.,Chen, G.Y.,Hung, A.W.,Hill, J. (deposition date: 2015-05-27, release date: 2015-06-17, Last modification date: 2023-11-08) |
Primary citation | Chen, G.Y.,Ng, F.M.,Tan, Y.W.,Poulsen, A.,Seetoh, W.,Lin, G.,Kang, C.,Then, S.W.,Ahmad, N.H.,Wong, Y.L.,Ng, H.,Chia, B.C.S.,Lau, Q.Y.,Hill, J.,Hung, A.W.,Keller, T.H. Application of Fragment-based Drug Discovery against DNA GyraseB To be published, |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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