5AIK
Human DYRK1A in complex with LDN-211898
Summary for 5AIK
Entry DOI | 10.2210/pdb5aik/pdb |
Related | 5AIL |
Descriptor | DYRK1A DUAL-SPECIFICITY TYROSINE-PHOSPHORYLATION REGULATED KINASE 1A, 4-(7-METHOXY-1-(TRIFLUOROMETHYL)-9H-PYRIDO[3,4-B]INDOL-9-yl)butan-1-amine, PHOSPHATE ION, ... (4 entities in total) |
Functional Keywords | transferase, dyrk1a, kinase |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 4 |
Total formula weight | 180511.82 |
Authors | Elkins, J.M.,Soundararajan, M.,Muniz, J.R.C.,Cuny, G.,Higgins, J.,Edwards, A.,Bountra, C.,Knapp, S. (deposition date: 2015-02-15, release date: 2015-02-25, Last modification date: 2024-01-10) |
Primary citation | Elkins, J.M.,Soundararajan, M.,Muniz, J.R.C.,Cuny, G.,Higgins, J.,Edwards, A.,Bountra, C.,Knapp, S. Dyrk1A with Ldn-211898 To be published, |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
Download full validation report