4ZW2

Crystal structure of the Mouse voltage gated calcium channel beta subunit isoform 1a in complex with Alpha Interaction Domain peptide.

Summary for 4ZW2

Entry DOI	10.2210/pdb4zw2/pdb
Descriptor	Voltage-dependent L-type calcium channel subunit beta-1,Voltage-dependent L-type calcium channel subunit beta-1, Voltage-dependent L-type calcium channel subunit alpha-1S, TRIETHYLENE GLYCOL, ... (4 entities in total)
Functional Keywords	dihydropyridine receptor, cavbeta, excitation contraction coupling, alpha interacting domain, metal transport
Biological source	Mus musculus (Mouse) More
Cellular location	Cell membrane, sarcolemma ; Peripheral membrane protein ; Cytoplasmic side : Q8R3Z5 Cell membrane, sarcolemma ; Multi-pass membrane protein : Q02789
Total number of polymer chains	2
Total formula weight	40072.79
Authors	Norris, N.C.,Oakley, A.J. (deposition date: 2015-05-19, release date: 2016-06-01, Last modification date: 2023-09-27)
Primary citation	Norris, N.C.,Joseph, S.,Aditya, S.,Karunasekara, Y.,Board, P.G.,Dulhunty, A.F.,Oakley, A.J.,Casarotto, M.G. Structural and biophysical analyses of the skeletal dihydropyridine receptor beta subunit beta 1a reveal critical roles of domain interactions for stability. J. Biol. Chem., 292:8401-8411, 2017 Cited by PubMed: 28351836 DOI: 10.1074/jbc.M116.763896 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.86 Å)

Structure validation